Sep, 26 2025
When President Donald Trump said on Sunday that he believes acetaminophen – sold as Tylenol or paracetamol – is "a very big factor" in autism, the comment sparked an immediate uproar. Health specialists, autism researchers, and advocacy groups rushed to point out that the claim is not backed by solid science. The controversy matters because the drug is one of the most widely used medicines during pregnancy, with roughly 50% of expectant parents taking it at some point.
Leading autism experts stress that the current body of research does not prove a causal link between maternal acetaminophen use and autism spectrum disorder. James Cusack, chief executive of the UK charity Autistica and an autistic individual himself, warned that "there is no definitive evidence to suggest that paracetamol use in mothers is a cause of autism." He added that when studies do hint at a connection, the effect size is "very, very small" and could easily be explained by other factors.
Large epidemiological investigations have explored possible associations, but results are inconsistent and often confounded by variables like infection, fever, or other medications taken during pregnancy. The scientific consensus remains that autism is a complex condition influenced by a mix of genetic and environmental elements, and that isolating a single drug as a primary driver oversimplifies the issue.
In the context of public health, experts caution that unfounded alarms could lead pregnant people to avoid a medication that is generally considered safe when used as directed. "People are looking for simple answers to a complicated problem," Cusack said, emphasizing that fear‑mongering can do more harm than good.
According to multiple reports, the Trump administration was preparing an announcement that would highlight concerns about a potential link between acetaminophen and autism, especially for pregnant women. During a White House press briefing, press secretary Karoline Leavitt declined to share details, calling the move a "powerful display" of the administration’s commitment to tackling root causes of chronic conditions.
When reporters asked whether the announcement might sow confusion, Leavitt urged caution, saying the media should not jump to conclusions before official findings are released. The lack of transparency fuels skepticism among scientists, who argue that any policy based on unverified claims could undermine trust in public health guidance.
For now, the medical community urges pregnant people to continue following established guidelines and to discuss any medication concerns with their health providers. The debate underscores the need for clear, evidence‑based communication, especially when it involves a pain reliever used by half of the world’s pregnant population.
As the discussion unfolds, researchers remain focused on gathering high‑quality data that can genuinely illuminate the myriad factors contributing to autism. Until then, the prevailing message from the scientific field is clear: there is no proven acetaminophen autism link, and caution should be exercised before drawing sweeping conclusions about widely used drugs.
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